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Messi himself is coming up against one of his favourite opponents. In the 41 games he's played against them, he has scored 32 goals.

Saturday's meeting, though, is crucial for Barcelona 's aspirations this season and they already cannot afford another loss. Starting defender Gerard Pique came off with a leg injury, and it was a nasty one, as his knee bent following a collision.

Now, we don't want to speculate as to what the injury is or its severity, but that doesn't look good at all.

Pique is a club legend and even though his level of play has been inconsistent this season, it's hard to imagine what Barcelona will look like if he's forced to miss a lengthy spell.

Not our night. SergiRoberto10 has a right quadriceps injury. They will both undergo further testing to determine the exact extent of their injuries.

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C'est la pause au Wanda Metropolitano! But de Y. La barre transversale de Llorente!!! He plays a wonderful through ball for Lionel Messi inside the box but from an acute angle he can only force a decent save from Jan Oblak.

Pedri was an option inside the box, but who are we to question when Messi should or should not shoot? Carrasco escapes down the left, and his low ball into the box looks destined to be tapped in by Angel Correa before Jordi Alba makes a crucial interception.

That Hermoso yellow card? It was in fact in him getting rescinded a yellow as it was he that was booked and not Carrasco earlier.

So still just the two bookings for Atleti. I'll let you know if that's not the case. It's gone a bit scrappy after an excellent first 15 minutes.

I was hoping up to that point that we were seeing a new free flowing style from Simeone. Just a false dawn by the look of it.

They are still in the bunker defending. Hosts are looking well organised at the back. Lionel Messi plays Demebele into space again down the right but with Griezmann waiting inside the box for a cross and a tap-in, Dembele's low ball is crucially turned behind for a corner - one Atleti clear.

Atleti's football has been outstanding so far. A slick passing move finds Marcos Llorente inside the box but his rising drive crashes off the top of the crossbar and out for a goal kick.

Koke purposefully stops an attack by pulling him down on the corner of the penalty box to pick up the game's first yellow card. Now Atleti build down the left where Yannick Carrasco squares for Saul Niguez 25 yards, whose first time top corner bound strike is very well beaten behind by Marc Ander ter-Stegen.

Ousmane Dembele makes a wonderful run to receive a pass on the right flank before he plays a cross to the near post. Former Atleti star Antoine Griezmann gets on the end of it but under heavy pressure he can only divert it over the crossbar.

Incredibly it's been 10 years since Atletico Madrid defeated Barcelona in the league. Will today be the day?

Barcelona of course have two games in hand with many of the teams above them - three with Villarreal so we can expect them to make a march from 10th.

Of course the headline there is Real Madrid dropping points again with a draw at Villarreal. It was the hosts who will perhaps be ruing the result more though as they miss out on the chance to go top.

Spanish football is back and they don't come much more bigger than Atletico Madrid vs Barcelona.